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Cerebral Amyloid Angiopathy and Atrial Fibrillation: An up to Date Case Report

Umberto Battistin1, Noora AlQassim1, Yusuf Hallak1

  • 1College of Medicine, Mohammad Bin Rashid University of Medicine and Health Sciences, Dubai, UAE.

The Neurohospitalist
|April 14, 2022
PubMed

Insights

Managing patients with concurrent Cerebral Amyloid Angiopathy (CAA) and atrial fibrillation presents a challenge. Balancing anticoagulation for atrial fibrillation against hemorrhage risk from CAA requires careful consideration and multidisciplinary input.

Area of Science:

  • Neurology
  • Cardiology
  • Geriatrics

Background:

  • Concurrent Cerebral Amyloid Angiopathy (CAA) and atrial fibrillation (AF) pose a growing clinical challenge, particularly in aging populations.
  • Managing these conditions requires balancing the risk of ischemic stroke from AF against the risk of intracerebral hemorrhage from CAA.

Observation:

  • A case report details a 67-year-old woman with AF on rivaroxaban experiencing transient neurological deficits.
  • These deficits were diagnosed as amyloid spells, indicating concomitant CAA.

Findings:

  • The case highlights the dilemma of anticoagulation in patients with both AF and CAA.
  • Current literature lacks a clear consensus on optimal anticoagulation management for such patients.

Implications:

  • Optimal management necessitates a multidisciplinary team approach.
  • Further research is needed to establish evidence-based guidelines for anticoagulation in patients with concurrent AF and CAA.

Keywords:
amyloid spellsanticoagulationatrial fibrillationcase reportcerebral amyloid angiopathy

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