Related Experiment Video
Updated: Sep 27, 2025
Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
An Unusual Case of Pemphigus Vulgaris
Laura Marano1, Gabriella Fabbrocini1, Giuseppe Monfrecola1
1Department of Clinical Medicine and Surgery, Section of Dermatology, University Hospital Federico II of Naples, Naples, Italy.
Introduction:
Pemphigus is a potential life-threatening skin disorder belonging to the group of the autoimmune bullous diseases affecting the skin and mucosa. The most common subtypes are pemphigus foliaceus (PF) and pemphigus vulgaris.
Case Presentation:
We present the case of a young woman with scalp manifestations diagnosed as seborrhiasis who came to our office where a more careful history and clinical examination directed us toward another diagnostic suspicion. The histological examination confirmed our suspicion of pemphigus and therefore we believe it is important to report our experience to avoid misdiagnosis.
Discussion/Conclusion:
Our case may be useful in the literature to identify cases of PF with atypical manifestations that may mimic other diseases.
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