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Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...

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Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting

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Copper-based nanomaterials for cancer theranostics.

Xiaoyan Zhong¹, Xingliang Dai², Yan Wang³

¹School of Public Health, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Suzhou Medical College of Soochow University, Suzhou, China.

Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology

|April 14, 2022

Summary

Copper-based nanomaterials show promise for cancer diagnosis and therapy. This review details their synthesis, properties, and applications in advanced imaging and combined treatments for improved cancer care.

Keywords:

Cu-based NMs cancer imaging cancer therapy combination therapy tumor microenvironment

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Area of Science:

Biomedical Engineering
Materials Science
Oncology

Background:

Copper-based nanomaterials (Cu-based NMs) exhibit favorable biocompatibility and unique properties, making them highly researched for biomedical applications.
Cu-based NMs are a significant focus in cancer treatment and diagnosis due to recent advancements in nanomedicine.

Purpose of the Study:

To review the classification and synthesis strategies of Cu-based NMs.
To summarize the applications of Cu-based NMs in biomedicine, focusing on imaging and therapy.
To discuss the challenges and future prospects for clinical translation of Cu-based NMs as theranostic agents.

Main Methods:

Classification and synthesis of Cu-based NMs.
Review of applications in biomedical imaging (photoacoustic, positron emission tomography, multimodal).
Analysis of therapeutic applications including monotherapies (photothermal therapy, chemodynamic therapy) and combined therapies.

Main Results:

Cu-based NMs demonstrate potential in various biomedical imaging modalities and therapeutic strategies.
Sophisticated design of Cu-based NMs enhances their capabilities for multimodal cancer diagnosis and therapy.
Combined therapies using Cu-based NMs show promise for improving cancer treatment efficiency.

Conclusions:

Cu-based NMs are versatile theranostic agents with significant potential in oncology.
Understanding the structure-property-activity relationship is crucial for rational design.
Further research and development are needed for successful clinical translation of Cu-based NMs.