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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Related Experiment Video

Updated: Sep 27, 2025

Iris Fixation via External Pentagram Suturing
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Endocapsular artificial iris implantation for iris defects: Reducing symptoms, restoring visual function and

Alexandra Z Crawford1,2, Simone E N Freundlich1,2, Joevy Lim1,2

  • 1Department of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.

Clinical & Experimental Ophthalmology
|April 14, 2022
PubMed
Summary

Endocapsular artificial iris implantation offers good cosmetic and functional results for iris defect repair. The procedure demonstrates a low risk of severe complications, with high patient satisfaction regarding appearance.

Keywords:
artificial endocapsular iris implantartificial irisiris colouriris defectiris melanoma

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Area of Science:

  • Ophthalmology
  • Ophthalmic Surgery

Background:

  • Iris defects can result from various conditions including melanotic lesions, trauma, and congenital anomalies.
  • Restoration of iris function and cosmesis is crucial for patient quality of life.

Purpose of the Study:

  • To evaluate the efficacy and safety of endocapsular artificial iris implantation for repairing iris defects.
  • To assess visual outcomes, complication rates, and patient satisfaction following the procedure.

Main Methods:

  • A retrospective case series of 18 patients who underwent endocapsular artificial iris implantation.
  • Data collected included patient demographics, surgical indications, postoperative visual acuity, intraocular pressure, and complications.
  • Follow-up duration was a minimum of 3 months, with an average of 14.1 months.

Main Results:

  • Nineteen artificial irises were implanted for indications including melanotic lesion excision, trauma, and congenital aniridia.
  • No significant changes in best corrected visual acuity (BCVA) or intraocular pressure (IOP) were observed postoperatively.
  • Common complications included transiently elevated IOP (42.1%) and mild prosthesis vaulting (15.7%). Severe complications were rare, affecting 5.3% of patients.
  • Cosmetic satisfaction was high, with 94.4% of patients expressing significant satisfaction.

Conclusions:

  • Endocapsular artificial iris implantation is a safe and effective method for restoring iris function and appearance.
  • The procedure yields favorable functional and cosmetic outcomes with a manageable complication profile.
  • High patient satisfaction underscores the value of this surgical intervention for iris defects.