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Updated: Sep 27, 2025
Destabilization of the Medial Meniscus and Cartilage Scratch Murine Model of Accelerated Osteoarthritis
Published on: July 6, 2022
Minimum 2-Year Clinical Outcomes of Medial Meniscus Root Tears in Relation to Coronal Alignment
Taylor J Ridley1,2, Joseph J Ruzbarsky1,2, Grant J Dornan1
1Steadman Philippon Research Institute, Vail, Colorado, USA.
Background:
The effect of coronal plane alignment on the outcomes of repairs of the medial meniscus root remains unclear.
Hypothesis:
Increased preoperative varus alignment is associated with higher failure rates and lower patient-reported outcomes (PROs) after isolated repair of the medial meniscus root.
Study Design:
Case series; Level of evidence, 4.
Methods:
Patients aged 18 years or older who underwent arthroscopy-assisted repair of the medial posterior meniscus root over a 7-year period were included. The mechanical axis of the knee was measured preoperatively. Osteoarthritis was assessed radiographically preoperatively and at the final follow-up according to the Kellgren-Lawrence grading scale. Failure was defined as any patient having to undergo revision root repair, partial meniscectomy of the previously repaired meniscus, debridement, lysis of adhesions, or conversion to arthroplasty.
Results:
A total of 53 patients (29 women, 24 men) with a mean age of 51.3 years were included in the follow-up analysis. The mean time of follow-up after surgery was 3.3 years (range, 22-77 months). Significant improvements were observed in all PROs analyzed. Decreased varus as measured by alignment percentage was correlated with baseline Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain (P = .023) and WOMAC Stiffness (P = .022). Alignment percentage was also significantly negatively correlated with postoperative WOMAC Stiffness (P = .005) and positively correlated with Lysholm (P = .003) and International Knee Documentation Committee (P = .009) scores. Higher baseline Kellgren-Lawrence grade was correlated with worse postoperative PROs (P < .05), except 12-Item Short Form Health Survey Mental Component Summary and satisfaction. Eight patients who underwent a concomitant high tibial osteotomy (HTO) achieved lower PROs in all scales analyzed, regardless of their alignment. When excluding patients who underwent HTO, postoperative Lysholm score (P = .004) and postoperative WOMAC Stiffness (p = 0.014) were inferior among the patients with >5° of varus.
Conclusion:
Lower extremity alignment closest to neutral correlated with improved PROs. Patients who underwent a concurrent HTO had worse PROs than those who did not undergo HTO.
