Related Experiment Video
Updated: Sep 27, 2025
Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles
Published on: December 1, 2016
Managing Apoptosis in Lung Diseases using Nano-assisted Drug Delivery System
Monu K Shukla1, Amit Dubey2,3, Sadanand Pandey4
1Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan-173229, Himachal Pradesh, India.
Abstract:
Several factors exist that limit the efficacy of lung cancer treatment. These may be tumor-specific delivery of therapeutics, airway geometry, humidity, clearance mechanisms, presence of lung diseases, and therapy against tumor cell resistance. Advancements in drug delivery using nanotechnology based multifunctional nanocarriers, have emerged as a viable method for treating lung cancer with more efficacy and fewer adverse effects. This review does a thorough and critical examination of effective nano-enabled approaches for lung cancer treatment, such as nano-assisted drug delivery systems. In addition, to therapeutic effectiveness, researchers have been working to determine several strategies to produce nanotherapeutics by adjusting the size, drug loading, transport, and retention. Personalized lung tumor therapies using sophisticated nano modalities have the potential to provide great therapeutic advantages based on individual unique genetic markers and disease profiles. Overall, this review provides comprehensive information on newer nanotechnological prospects for improving the management of apoptosis in lung cancer.
Insights
Nanotechnology offers improved lung cancer treatment by enhancing drug delivery and reducing side effects. Advanced nanocarriers enable personalized therapies, targeting tumor resistance and improving patient outcomes.
Area of Science:
- Oncology
- Nanotechnology
- Drug Delivery
Background:
- Lung cancer treatment efficacy is limited by factors like poor drug delivery, tumor resistance, and individual patient profiles.
- Conventional therapies often face challenges in achieving targeted delivery and overcoming biological barriers within the lungs.
Approach:
- This review critically examines nano-enabled approaches for lung cancer treatment, focusing on multifunctional nanocarriers.
- Strategies for optimizing nanotherapeutics include tailoring size, drug loading, transport, and retention for enhanced efficacy.
Key Points:
- Nanotechnology-based drug delivery systems show promise for more effective lung cancer treatment with fewer adverse effects.
- Personalized lung tumor therapies utilizing nano modalities can leverage genetic markers and disease profiles for tailored treatment.
- Research is advancing nanotherapeutic strategies to improve apoptosis management in lung cancer.
Conclusions:
- Nano-enabled approaches represent a significant advancement in improving lung cancer treatment outcomes.
- Tailored nanomedicines hold potential for personalized oncology, addressing individual patient needs and improving therapeutic effectiveness.
