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Updated: Jun 11, 2026

Photodynamic Therapy with Blended Conducting Polymer/Fullerene Nanoparticle Photosensitizers
Published on: October 28, 2015
Fullerene-porphyrin hybrid nanoparticles that generate activated oxygen by photoirradiation
Kouta Sugikawa1, Kosuke Masuda1, Kentaro Kozawa1
1Applied Chemistry Program, Graduate School of Advanced Science and Engineering, Hiroshima University Higashi-Hiroshima 739-8527 Japan sugikawa@hiroshima-u.ac.jp aikeda@hiroshima-u.ac.jp.
Abstract:
The preparation of water-dispersible hybrid nanoparticles comprising fullerene and porphyrin from cyclodextrin complexes is described. In the presence of polyethylene glycol, C60 fullerene and porphyrin were expelled from the cyclodextrin cavity to form fullerene-porphyrin hybrid nanoparticles in water. The fullerene-porphyrin hybrid nanoparticles exhibit improved singlet oxygen generation ability under photoirradiation compared with that of C60 nanoparticles.
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