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Enzyme-functionalised, core/shell magnetic nanoparticles for selective pH-triggered sucrose capture.

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Summary

This study developed a nanomaterial to selectively capture sucrose from food, creating low-calorie options. The reusable material offers a novel approach to reduce sugar intake and combat obesity and diabetes.

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Area of Science:

  • Materials Science
  • Biotechnology
  • Food Science

Background:

  • Diabetes and obesity are global health concerns linked to high calorie intake.
  • Reducing dietary sugar, particularly sucrose, is a key strategy for managing these conditions.
  • Existing methods for sugar reduction in food are limited.

Purpose of the Study:

  • To develop a novel nanomaterial for the selective capture and removal of sucrose from food products.
  • To create a tool for producing low-calorie beverages and healthier food options.
  • To investigate the efficiency, reusability, and recovery of the developed nanomaterial.

Main Methods:

  • Synthesis of magnetite nanoparticles (Fe3O4 NPs) coated with silica (SiO2).
  • Immobilization of the enzyme invertase onto the functionalized nanomaterial surface.
  • pH-triggered sucrose capture at pH 3.0 and subsequent hydrolysis of captured sucrose at pH 4.8.
  • Magnetic separation and reusability testing of the nanomaterial.

Main Results:

  • The developed nanomaterial demonstrated high selectivity and efficiency in capturing sucrose (13.5 mmol L-1 per gram).
  • The nanomaterial was successfully reused for ten cycles with no loss of sucrose-capturing capability.
  • Captured sucrose was recovered as inverted sugar, a valuable product, and the nanomaterial facilitated the creation of low-sugar beverages.

Conclusions:

  • The developed functionalized nanomaterial offers a promising technology for selective sucrose removal from food and beverages.
  • This innovation supports the commercialization of low-calorie food products, promoting healthier consumer choices.
  • The technology contributes to public health by aiding in the fight against diabetes and obesity.