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Ion-doped mesoporous bioactive glass: preparation, characterization, and applications using the spray pyrolysis
Andualem Belachew Workie1, Eyob Messele Sefene1
1Faculty of Mechanical and Industrial Engineering, Bahir Dar Institute of Technology, Bahir Dar University P.O. Box 26 Bahir Dar Ethiopia andualembelachew2@gmail.com eyobsmart27@gmail.com Eyob.Messele@bdu.edu.et +251-910-894795 +251-918-161601.
RSC Advances
|April 15, 2022
Summary
Zinc-doped bioglass (Zn-BG) shows promise for medical applications due to its biocompatibility and ability to form hydroxyl carbonate apatite. Spray pyrolysis is an effective method for synthesizing Zn-BG for advanced medical uses.
Area of Science:
- Biomaterials Science
- Biotechnology
- Materials Chemistry
Background:
- Biotechnology applications span medical procedures, dentistry, biosensors, and drug delivery systems.
- Biocompatible glasses, like bioglass (BG), are suitable for permanent implantation and promote hydroxyl carbonate apatite formation due to their porosity and high surface area.
- Zinc-doped bioglass (Zn-BG) offers potential for enhanced medical applications.
Purpose of the Study:
- To explore the synthesis of Zn-doped bioglass (Zn-BG) for medical applications.
- To highlight the effectiveness of spray pyrolysis as a fabrication method for Zn-BG.
- To emphasize the importance of material characterization for clinical utility.
Main Methods:
- Various fabrication techniques for BG matrixes are discussed, including melt-quenching, sol-gel, spray drying, modified Stöber, and spray pyrolysis.
- Spray pyrolysis is detailed as a versatile, low-cost, non-vacuum method suitable for producing powders and films.
- The method is adaptable for large-area deposition and industrial-scale production.
Main Results:
- Spray pyrolysis is identified as a comprehensive, effective, and versatile material synthesis technology.
- The technique allows for the production of materials in powder and film forms on various substrates.
- The process is amenable to industrial scaling and large-area deposition.
Conclusions:
- Zn-doped bioglass (Zn-BG) synthesis is achievable through various methods, with spray pyrolysis being particularly advantageous.
- Characterization using techniques like SEM, TEM, BET, and XRD is crucial for evaluating MBG fabricated in the lab for medical use.
- The properties of Zn-BG, including biocompatibility and apatite formation, support its potential in advanced medical treatments.
