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Updated: Sep 27, 2025
Engineering Antiviral Agents via Surface Plasmon Resonance
Published on: June 14, 2022
Hyperpolarization study on remdesivir with its biological reaction monitoring via signal amplification by reversible
Hye Jin Jeong1, Sein Min2, Sarah Kim2
1Department of Physics and Chemistry, Korea Military Academy Seoul 01805 South Korea doas1mind@kma.ac.kr.
Abstract:
Our experiments indicate hyperpolarized proton signals in the entire structure of remdesivir are obtained due to a long-distance polarization transfer by para-hydrogen. SABRE-based biological real-time reaction monitoring, by using a protein enzyme under mild conditions is carried out. It represents the first successful para-hydrogen based hyperpolarization application in biological reaction monitoring.
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