Highly efficient synthesis of 3,4-diarylbutadiene sulfones using Heck-Matsuda reaction
Olga V Shurupova1, Sergey A Rzhevskiy1, Lidiya I Minaeva1
1A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Leninsky Prospect 29 Moscow 119991 Russia aasachenko@ips.ac.ru.
Abstract:
For the first time we describe a general method for the synthesis of previously not synthesized unsymmetrical 3,4-diarylbutadiene sulfones which can be stable convenient precursors for 2,3-diaryl-1,3-butadienes. Our method for arylation of butadiene sulfones via Heck-Matsuda reaction allows to obtain unsymmetrical 3,4-diarylbutadiene sulfones with a variety of alkyl, alkoxy, nitro, ethoxycarbonyl, perfluoroalkyl and halogen substituents (30 examples) in very good yields using readily available reagents and catalysts.
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