Application of Intra-articular Corticosteroid Injection in Juvenile Idiopathic Arthritis

Sha Li1, Wei Zhang1, Yan Lin2

  • 1Department of Rheumatology, The Affiliated Women's and Children's Hospital, School of Medicine UESTC, Chengdu Women and Children's Central Hospital, Chengdu, China.

Insights

Intra-articular corticosteroid injections (IACIs) effectively treat juvenile idiopathic arthritis (JIA) by reducing joint inflammation and improving function. This review guides optimal IACIs use in children, covering techniques, efficacy, and safety.

Area of Science:

  • Pediatric Rheumatology
  • Pediatric Orthopedics

Background:

  • Juvenile idiopathic arthritis (JIA) is a leading cause of childhood disability, characterized by persistent synovitis and joint pain.
  • JIA significantly impacts children's quality of life due to reduced range of motion, deformity, and gait disturbances.

Purpose of the Study:

  • To review and guide the optimal use of intra-articular corticosteroid injections (IACIs) for treating JIA in children.
  • To provide a comprehensive overview of IACIs, including case selection, techniques, efficacy, and safety.

Main Methods:

  • Literature review focusing on IACIs in pediatric JIA.
  • Analysis of case selection, drug and dose selection, anesthesia, injection techniques, and ultrasound guidance.
  • Evaluation of efficacy, recurrence, influencing factors, post-injection physiotherapy, safety, and complications.

Main Results:

  • IACIs offer localized anti-inflammatory effects, minimizing systemic adverse reactions.
  • IACIs can prevent or treat joint contractures, Baker's cysts, and tenosynovitis, improving function and gait.
  • Ultrasound guidance enhances the safety and efficacy of IACIs in pediatric JIA.

Conclusions:

  • IACIs are a crucial treatment modality for JIA, offering significant benefits for joint function and quality of life.
  • This review provides evidence-based guidance for the effective and safe application of IACIs in pediatric patients.
  • Optimizing IACIs involves careful case selection, appropriate techniques, and comprehensive post-injection management.

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