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Published on: May 26, 2023
Application of Intra-articular Corticosteroid Injection in Juvenile Idiopathic Arthritis
1Department of Rheumatology, The Affiliated Women's and Children's Hospital, School of Medicine UESTC, Chengdu Women and Children's Central Hospital, Chengdu, China.
Insights
Intra-articular corticosteroid injections (IACIs) effectively treat juvenile idiopathic arthritis (JIA) by reducing joint inflammation and improving function. This review guides optimal IACIs use in children, covering techniques, efficacy, and safety.
Area of Science:
- Pediatric Rheumatology
- Pediatric Orthopedics
Background:
- Juvenile idiopathic arthritis (JIA) is a leading cause of childhood disability, characterized by persistent synovitis and joint pain.
- JIA significantly impacts children's quality of life due to reduced range of motion, deformity, and gait disturbances.
Purpose of the Study:
- To review and guide the optimal use of intra-articular corticosteroid injections (IACIs) for treating JIA in children.
- To provide a comprehensive overview of IACIs, including case selection, techniques, efficacy, and safety.
Main Methods:
- Literature review focusing on IACIs in pediatric JIA.
- Analysis of case selection, drug and dose selection, anesthesia, injection techniques, and ultrasound guidance.
- Evaluation of efficacy, recurrence, influencing factors, post-injection physiotherapy, safety, and complications.
Main Results:
- IACIs offer localized anti-inflammatory effects, minimizing systemic adverse reactions.
- IACIs can prevent or treat joint contractures, Baker's cysts, and tenosynovitis, improving function and gait.
- Ultrasound guidance enhances the safety and efficacy of IACIs in pediatric JIA.
Conclusions:
- IACIs are a crucial treatment modality for JIA, offering significant benefits for joint function and quality of life.
- This review provides evidence-based guidance for the effective and safe application of IACIs in pediatric patients.
- Optimizing IACIs involves careful case selection, appropriate techniques, and comprehensive post-injection management.
Abstract:
Juvenile idiopathic arthritis (JIA) is one of the common rheumatic diseases in pediatrics. Persistent synovitis and joint pain cause reduced range of motion, deformity and gait interruption, which are important reasons for children's disability and a decline in their quality of life. Rheumatology experts have explored good treatment strategies, among which intra-articular corticosteroid injections (IACIs) targeting joints can greatly reduce these systemic adverse reactions while still obtaining local anti-inflammatory effects. Local inhibition of synovitis by the use of steroid hormones in a joint cavity can avoid or reduce adverse reactions of systemic therapy, prevent or treat leg length variance and joint contracture, solve Baker's cyst, improve tenosynovitis, promote physical therapy and rehabilitation, make gait change smoothly, relieve pain, and restore joint function. Given the importance of IACIs in treating JIA, this paper reviewed the case selection, drug injection, dose selection, current anesthesia and injection techniques, the efficacy, recurrence, and influencing factors of IACIs, the management of physiotherapy intervention post-injection, the application of ultrasound guidance and the safety and complications of IACIs in children with JIA. This study aims to guide the use of IACIs for the best approach throughout the review.
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