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Updated: Sep 27, 2025

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Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation
Published on: June 13, 2025
196
Proximal humerus reconstruction in orthopedic oncology
Sridhar Pinnamaneni1, Timothy A Damron2
1Shoulder and Elbow Section, Signature Orthopedics, St. Louis, Missouri 63128, USA.
Summary
Reconstructive options for proximal humeral bone tumors have advanced, with reverse total shoulder arthroplasty (RTSA) becoming more common than hemiarthroplasty. This review covers various techniques, outcomes, and complications.
Area of Science:
- Orthopedic surgery
- Oncology
- Reconstructive surgery
Background:
- Proximal humeral malignancies necessitate radical resection and reconstruction.
- Surgical options have evolved significantly over time.
- Reverse total shoulder arthroplasty (RTSA) is increasingly utilized.
Purpose of the Study:
- To review reconstructive options for proximal humeral bone tumors.
- To compare different techniques including RTSA, hemiarthroplasty, allografts, and megaprostheses.
- To analyze indications, techniques, complications, and outcomes.
Main Methods:
- Literature review of reconstructive techniques for proximal humeral bone tumors.
- Analysis of case-based pictorial presentations.
- Evaluation of published results, complications, and indications.
Main Results:
- Reverse total shoulder arthroplasty (RTSA) is increasingly favored over hemiarthroplasty.
- Proximal humeral allograft-prosthetic composites, megaprostheses, and osteoarticular allografts are viable options.
- The review details the specific applications and outcomes of each reconstructive method.
Conclusions:
- A range of reconstructive options exist for proximal humeral bone tumor resection.
- Reverse total shoulder arthroplasty (RTSA) represents a significant advancement in this field.
- Understanding the indications, techniques, and outcomes is crucial for optimal patient management.
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