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Peptide-pro complex serum: Investigating effects on aged skin.
Melissa Moy1, Isabel Diaz2, Ewelina Lesniak1
1Research and Development, Colgate-Palmolive Company, Piscataway, New Jersey, USA.
Journal of Cosmetic Dermatology
|April 15, 2022
Summary
This study shows a new facial serum significantly improves aged skin. The anti-aging serum reduces wrinkles and roughness, boosts hydration, and thickens skin for a smoother appearance.
Area of Science:
- Dermatology
- Cosmetic Science
- Skin Biology
Background:
- Aging skin presents a significant unmet consumer need for effective treatments.
- Topical anti-aging solutions are in high demand within the cosmetic industry.
Purpose of the Study:
- To evaluate the efficacy of a novel topical facial serum on aged skin.
- The serum contains a proprietary blend of neuropeptides, proteins, amino acids, and marine extracts.
- Assessments included ex vivo and clinical studies.
Main Methods:
- Ex vivo comparison of the serum against a market competitor and an untreated control using microrelief, smoothness, and epidermal thickness.
- A 12-week clinical study where subjects used the serum on their entire face, serving as their own control.
- Skin hydration, imaging, dermatological evaluation for tolerability and efficacy, and a subject questionnaire were employed.
Main Results:
- Significant reduction in microfolds and skin roughness, with increased epidermal thickness compared to controls.
- Statistically significant improvement in skin moisturization from baseline.
- Clinically significant improvements in skin smoothness, wrinkle severity, fine line visibility, and noticeable lifting/tightening effects.
Conclusions:
- The facial serum demonstrated significant improvements in aged skin quality.
- The proprietary blend of ingredients effectively rejuvenates aging skin.
- Ex vivo and clinical data support the serum's anti-aging benefits.
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