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Updated: Sep 27, 2025

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Engineered Vascularized Muscle Flap
Published on: January 11, 2016
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[Imaging study and clinical application of peroneal perforating chimeric tissue flap]
Ziyang Zhang1, Wenhu Jin1, Hui Quan1
1Department of Burn and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi Guizhou, 563003, P. R. China.
Summary
The peroneal perforating chimeric tissue flap is a safe and reliable option for reconstructing composite calf and heel defects. This technique demonstrates consistent vessel distribution and positive clinical outcomes, aiding in limb salvage.
Area of Science:
- Orthopedic Surgery
- Vascular Surgery
- Reconstructive Surgery
Background:
- Composite defects of the calf and heel pose significant reconstructive challenges.
- Effective tissue flaps are crucial for restoring function and form in lower limb injuries.
Purpose of the Study:
- To assess the feasibility and clinical efficacy of the peroneal perforating chimeric tissue flap for composite calf and heel defect repair.
- To analyze the anatomical distribution of peroneal artery perforators using lower limb angiography.
Main Methods:
- Lower limb digital subtraction angiography was performed on 50 patients to map peroneal artery perforator anatomy.
- The peroneal perforating chimeric tissue flap was designed and applied to repair 7 cases of composite calf and heel defects (April 2015-October 2020).
- Flap survival, wound healing, and functional outcomes were evaluated postoperatively.
Main Results:
- Peroneal artery perforators showed consistent anatomical distribution, primarily in four specific locations.
- All 7 peroneal perforating chimeric tissue flaps survived, with complete wound healing by first intention.
- Bone graft healing was successful (6-11 months), with good functional recovery (Holden walking function score grade IV-V in all patients).
Conclusions:
- The peroneal perforating vessel anatomy is predictable, supporting the use of this flap.
- The peroneal perforating chimeric tissue flap is a safe, reliable, and effective method for reconstructing composite calf and heel defects.

