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Updated: Sep 26, 2025

Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy
Published on: March 16, 2020
Effective forces between active polymers
1Department of Chemistry, Columbia University, 3000 Broadway, New York, New York 10027, USA.
Abstract:
The characterization of the interactions between two fully flexible self-avoiding polymers is one of the classic and most important problems in polymer physics. In this paper we measure these interactions in the presence of active fluctuations. We introduce activity into the problem using two of the most popular models in this field, one where activity is effectively embedded into the monomers' dynamics, and the other where passive polymers fluctuate in an explicit bath of active particles. We establish the conditions under which the interaction between active polymers can be mapped into the classical passive problem. We observe that the active bath can drive the development of strong attractive interactions between the polymers and that, upon enforcing a significant degree of overlap, they come together to form a single double-stranded unit. A phase diagram tracing this change in conformational behavior is also reported.
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