Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

705
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
705
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

340
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
340
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

452
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
452
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

477
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
477
What is the Immune System?01:38

What is the Immune System?

117.8K
Overview
117.8K
Special Features of Adaptive Immunity01:20

Special Features of Adaptive Immunity

1.2K
The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessing the combined effects of Black Cohosh, Soy Isoflavones, and SDG Lignans on menopausal symptoms: a randomized, double-blind, placebo-controlled clinical trial.

European journal of nutrition·2025
Same author

Phase 2-3 Trial: Prevention of the Progression to Moderate and Severe COVID-19 in SARS-CoV-2-Infected Non-Hospitalized Adults With Inhaled siRNA-Based MIR 19.

Allergy·2025
Same author

Incidence of socially significant infectious diseases (HIV, TB and HIV/TB coinfection) in the Arctic regions of Russia).

International journal of circumpolar health·2021
Same author

Diagnostics and management of tuberculosis and COVID-19 in a patient with pneumothorax (clinical case).

Journal of clinical tuberculosis and other mycobacterial diseases·2021
Same author

New laboratory criteria of the autoimmune inflammation in pulmonary sarcoidosis and tuberculosis.

Clinical immunology (Orlando, Fla.)·2021
Same author

Imbalance in B cell and T Follicular Helper Cell Subsets in Pulmonary Sarcoidosis.

Scientific reports·2020

Related Experiment Video

Updated: Sep 26, 2025

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis
09:34

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis

Published on: August 16, 2021

1.9K

Tuberculosis and autoimmunity: Common features.

A Starshinova1, А Malkova2, I Kudryavtsev3

  • 1Head of the Research Department, Almazov National Medical Research Centre, 2, Akkuratov str, Saint-Petersburg, 197341, Russia.

Tuberculosis (Edinburgh, Scotland)
|April 17, 2022
PubMed
Summary

Tuberculosis infection may involve autoimmune inflammation, impacting treatment effectiveness. Addressing these autoimmune complications is crucial for predicting tuberculosis treatment outcomes.

Keywords:
ASIAAutoantibodiesAutoimmunityHLAMolecular mimicryTuberculosis

More Related Videos

Author Spotlight: Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis
06:57

Author Spotlight: Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis

Published on: May 12, 2023

2.6K
Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
12:59

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

Published on: September 26, 2013

34.8K

Related Experiment Videos

Last Updated: Sep 26, 2025

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis
09:34

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis

Published on: August 16, 2021

1.9K
Author Spotlight: Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis
06:57

Author Spotlight: Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis

Published on: May 12, 2023

2.6K
Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
12:59

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

Published on: September 26, 2013

34.8K

Area of Science:

  • Immunology
  • Infectious Diseases
  • Autoimmunity

Background:

  • Tuberculosis (TB) is primarily recognized as an infectious disease caused by Mycobacterium tuberculosis.
  • Emerging evidence suggests a significant autoimmune component in the pathogenesis and progression of TB infection.
  • Understanding this autoimmune aspect is vital for comprehensive TB management.

Purpose of the Study:

  • To review and synthesize current knowledge on the autoimmune manifestations in tuberculosis.
  • To explore the clinical and immunological signs associated with autoimmune inflammation in TB patients.
  • To highlight the potential role of Mycobacterium tuberculosis in triggering autoimmune processes.

Main Methods:

  • Literature review of recent studies on tuberculosis and autoimmunity.
  • Analysis of clinical case reports and immunological data.
  • Synthesis of findings regarding the interplay between infection and autoimmune responses.

Main Results:

  • Tuberculosis infection presents with both infectious and autoimmune inflammatory signs.
  • Clinical manifestations include a range of symptoms indicative of autoimmune processes.
  • Immunological studies reveal specific markers associated with autoimmune dysregulation in TB.

Conclusions:

  • The autoimmune component in tuberculosis is a significant factor influencing disease course.
  • Autoimmune complications can affect the efficacy of standard tuberculosis treatments.
  • Targeting autoimmune responses may be a critical therapeutic strategy for improving TB treatment outcomes and prognosis.