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Author Spotlight: Developing a Bedside Protocol for Kidney and Genitourinary Ultrasonography
Published on: June 21, 2024
Ultrasonographic reference values and a simple yet practical formula for estimating average kidney length in Japanese
Naoya Fujita1, Osamu Uemura2, Ryoko Harada3
1Department of Pediatric Nephrology, Aichi Children's Health and Medical Center, 426 7-chome, Morioka-cho, Obu, Aichi, 474-8710, Japan. fujita708@hkg.odn.ne.jp.
Insights
This study establishes reliable kidney length reference values and prediction formulas for Japanese children using ultrasonography. These findings aid in diagnosing and managing pediatric kidney diseases effectively.
Area of Science:
- Pediatric Nephrology
- Medical Imaging
- Biostatistics
Background:
- Accurate kidney size assessment is crucial for pediatric kidney disease management.
- Existing ultrasonographic reference values for kidney length in Japanese children lack robustness and sufficient sample size.
- There is a need for reliable diagnostic tools in pediatric nephrology.
Purpose of the Study:
- To establish detailed and simple ultrasonographic reference values for kidney length in Japanese children.
- To develop practical estimation formulas for average and lower limit of normal kidney length.
- To provide robust data for clinical practice in pediatric nephrology.
Main Methods:
- Retrospective analysis of ultrasonographic kidney measurements from 1984 Japanese children (aged ≤18 years).
- Development of detailed reference values by aggregating left/right kidneys separately for boys and girls.
- Creation of simple reference values and regression-based formulas for kidney length estimation.
Main Results:
- Established detailed and simple reference values for kidney length based on 3968 kidneys.
- Generated a formula for average kidney length: kidney length (cm) = body height (m) × 5 + 2.
- Developed a formula for the lower limit of normal kidney length in children under 130 cm height.
Conclusions:
- Established comprehensive ultrasonographic reference values for kidney length in Japanese children.
- Provided simple reference values and practical estimation formulas for clinical use.
- Aimed to improve the diagnosis and management of kidney diseases in pediatric populations.
Background:
The assessment of kidney size is essential for treating kidney disease. However, there are no reliable and sufficiently robust ultrasonographic reference values or prediction formulas for kidney length in Japanese children, based on a sufficient number of participants.
Methods:
We retrospectively analyzed kidney measurements by ultrasonography in children aged 18 years or younger from eight facilities throughout Japan between January 1991 and September 2018. Detailed reference values were developed by aggregating the left and right kidneys of boys and girls separately. Simple and practical reference values were developed by combining all the data from left and right kidneys and boys and girls. The estimation formulas for the average value and lower limit of the normal range for kidney length were developed based on regression analysis.
Results:
Based on the aggregated kidney length data of 1984 participants (3968 kidneys), detailed reference values and simple reference values for kidney length were determined. From the regression analysis, the formula for calculating the average kidney length was generated as "kidney length (cm) = body height (m) × 5 + 2", and that for predicting the lower limit of normal kidney length in children under 130 cm was calculated as "lower limit (cm) = 0.85 × [body height (m) × 5 + 2]".
Conclusion:
Detailed ultrasonographic reference values of kidney length for Japanese children and simple reference values and estimation formulas for daily practice have been established.
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