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Related Experiment Videos

The hand in metastatic disease.

R Kerin

    The Journal of Hand Surgery
    |January 1, 1987
    PubMed
    Summary

    Metastatic tumors in the hand are rare, accounting for just over 0.1% of primary tumors. Hand tumors can be the first sign of cancer elsewhere in the body, often originating from the lung, breast, or kidney.

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    Area of Science:

    • Oncology
    • Orthopedic Surgery
    • Radiology

    Background:

    • Metastases to the hand are uncommon, representing a small fraction of all cancer spread.
    • Understanding the patterns and origins of hand metastases is crucial for diagnosis and management.

    Observation:

    • A literature review identified 163 cases of metastatic tumors to the hand, with three new cases reported.
    • In over 16% of instances, a hand tumor was the initial presentation of a distant primary malignancy.
    • The lung, breast, and kidney are the most common primary sources for hand metastases.

    Findings:

    • The incidence of primary tumors metastasizing to the hand is slightly over 0.1%.
    • Terminal phalanges are the most common site for hand metastases, followed by metacarpals and proximal phalanges.
    • The exact mechanism of tumor cell dissemination to the hand remains unclear.

    Implications:

    • Early recognition of hand tumors as potential metastases can lead to earlier diagnosis of primary cancers.
    • Further research into the dissemination mechanisms may improve treatment strategies for metastatic bone disease.
    • This review highlights the importance of considering metastatic disease in the differential diagnosis of hand masses.

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