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Updated: Sep 26, 2025

A Murine Orthotopic Bladder Tumor Model and Tumor Detection System
Published on: January 12, 2017
Leiomyosarcoma of urinary bladder in a Shih Tzu dog
Jiyoung Park1,2, Aryung Nam3, Hae-Beom Lee4
1Ulsan S Animal Medical Center, Ulsan, South Korea.
Abstract:
A 10-year-old intact male Shih Tzu dog presented with hematuria. Double-contrast cystography revealed a polypoid filling defect at the apex of the urinary bladder. Ultrasonography revealed a heterogeneously hypoechoic intramural mass with minimal vascular flow beneath the submucosal layer. After partial cystectomy, a well-demarcated bladder leiomyosarcoma was diagnosed on histopathology. The patient was alive and well without any clinical signs, recurrence, or metastasis at the 29-month follow-up after the surgical removal of the bladder mass. Leiomyosarcoma should be considered as a differential diagnosis if mass-like lesions are observed in the urinary bladder, although this type of malignancy is rare in canines. Histopathological confirmation is important for predicting prognosis and determining further medical plans.
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