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Updated: Sep 26, 2025

Reconstruct Human Retinoblastoma In Vitro
Published on: October 11, 2022
Applications of Non-Coding RNAs in Patients With Retinoblastoma
Daniel Fernandez-Diaz1,2, Cristina Rodriguez-Vidal3, Paula Silva-Rodríguez2,4
1Department of Ophthalmology, University Hospital of Santiago de Compostela, Santiago de Compostela, Spain.
Abstract:
Retinoblastoma (RB) is the most common primary intraocular malignancy in childhood. In the carcinogenic process of neoplasms such as RB, the role of non-coding RNAs (ncRNAs) has been widely demonstrated recently. In this review, we aim to provide a clinical overview of the current knowledge regarding ncRNAs in relation to RB. Although ncRNAs are now considered as potential diagnostic biomarkers, prognostic factors, and therapeutic targets, further studies will facilitate enhanced understanding of ncRNAs in RB physiopathology and define the roles ncRNAs can play in clinical practice.
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