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Updated: Sep 26, 2025

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
Published on: March 21, 2025
Incidental prostate-specific membrane antigen-avid glioblastoma detected on 68Ga-prostate-specific membrane antigen
James Yuheng Jiang1, Christine Kang1, Paul Bui1
1Departments of Nuclear Medicine and PET, Nepean Hospital, Derby St, Kingswood NSW 2747, Australia.
Abstract:
A 74-year-old man was referred for a 68Ga-prostate-specific membrane antigen (PSMA) PET/CT scan for newly diagnosed prostate cancer which confirmed the presence of PSMA avid cancer in the right gland with no evidence of PSMA metastasis. Incidentally, there was a markedly PSMA avid (SUVmax 7.0) lobulated periventricular mass in the region of the left basal ganglia which was T2 hyperintense and T1 hypointense with perilesional oedema and vivid Gadolinium enhancement on MRI. The patient underwent stereotactic guided biopsy which confirmed LHD wild-type glioblastoma (WHO grade IV).

