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Primary hyperparathyroidism presenting with sudden onset paraplegia
Nur Aisyah Zainordin1, Awla Mohd Azraai2, Fatimah Zaherah Mohamad Shah1
1Endocrine Unit, Faculty of Medicine, University Technology MARA, Jalan Hospital, Sungai Buloh, Selangor.
SAGE Open Medical Case Reports
|April 18, 2022
Summary
A spinal tumor caused Brown
Area of Science:
- Endocrinology
- Neurosurgery
- Oncology
Background:
- Long-standing type 2 diabetes mellitus can present with neurological complications.
- Spinal tumors can cause significant neurological deficits.
Observation:
- A 48-year-old female with type 2 diabetes presented with acute bilateral lower limb weakness.
- Examination revealed paraplegia, sensory loss to T10, and reduced reflexes.
- Imaging identified a thoracic spinal mass compressing the spinal cord.
Findings:
- Histopathology confirmed a giant cell tumor of the spine.
- Ectopic parathyroid adenoma was identified, leading to Brown tumor.
- Surgical decompression and parathyroidectomy were performed.
- Biochemical normalization of calcium and parathyroid hormone occurred post-surgery.
Implications:
- Giant cell tumors of the spine require prompt diagnosis and management.
- Ectopic parathyroid adenomas can mimic other conditions and cause significant metabolic disturbances.
- Despite treatment, severe neurological deficits may persist, highlighting the importance of early intervention.
Keywords:
Primary hyperparathyroidismbrown tumourhyperparathyroidismparathyroid adenomaspinal stenosisMore Related Videos
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