A computer-aided diagnostic framework for coronavirus diagnosis using texture-based radiomics images

The accurate and rapid detection of the novel coronavirus infection, coronavirus is very important to prevent the fast spread of such disease. Thus, reducing negative effects that influenced many industrial sectors, especially healthcare. Artificial intelligence techniques in particular deep learning could help in the fast and precise diagnosis of coronavirus from computed tomography images. Most artificial intelligence-based studies used the original computed tomography images to build their models; however, the integration of texture-based radiomics images and deep learning techniques could improve the diagnostic accuracy of the novel coronavirus diseases. This study proposes a computer-assisted diagnostic framework based on multiple deep learning and texture-based radiomics approaches. It first trains three Residual Networks (ResNets) deep learning techniques with two texture-based radiomics images including discrete wavelet transform and gray-level covariance matrix instead of the original computed tomography images. Then, it fuses the texture-based radiomics deep features sets extracted from each using discrete cosine transform. Thereafter, it further combines the fused texture-based radiomics deep features obtained from the three convolutional neural networks. Finally, three support vector machine classifiers are utilized for the classification procedure. The proposed method is validated experimentally on the benchmark severe respiratory syndrome coronavirus 2 computed tomography image dataset. The accuracies attained indicate that using texture-based radiomics (gray-level covariance matrix, discrete wavelet transform) images for training the ResNet-18 (83.22%, 74.9%), ResNet-50 (80.94%, 78.39%), and ResNet-101 (80.54%, 77.99%) is better than using the original computed tomography images (70.34%, 76.51%, and 73.42%) for ResNet-18, ResNet-50, and ResNet-101, respectively. Furthermore, the sensitivity, specificity, accuracy, precision, and F1-score achieved using the proposed computer-assisted diagnostic after the two fusion steps are 99.47%, 99.72%, 99.60%, 99.72%, and 99.60% which proves that combining texture-based radiomics deep features obtained from the three ResNets has boosted its performance. Thus, fusing multiple texture-based radiomics deep features mined from several convolutional neural networks is better than using only one type of radiomics approach and a single convolutional neural network. The performance of the proposed computer-assisted diagnostic framework allows it to be used by radiologists in attaining fast and accurate diagnosis.