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Published on: May 25, 2020
Clinical Analysis of Pediatric Glaucoma in Central China
Qian Liu1, Changgeng Liu1, Haijun Li1
1Henan Eye Institute, Henan Eye Hospital, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, China.
Insights
This study details pediatric glaucoma in China, finding primary congenital glaucoma most common. Surgical interventions like trabeculotomy were frequent, highlighting the need for early diagnosis and public awareness.
Area of Science:
- Ophthalmology
- Pediatric Medicine
- Public Health
Background:
- Pediatric glaucoma is a significant cause of vision loss in children.
- Understanding the epidemiology and management of pediatric glaucoma is crucial for effective treatment strategies.
- Central China has a notable population of pediatric glaucoma cases requiring specific attention.
Purpose of the Study:
- To characterize the epidemiology, management, and outcomes of pediatric glaucoma in central China.
- To identify the most common subtypes and interventions for pediatric glaucoma in the region.
- To inform public health initiatives for early diagnosis and prevention.
Main Methods:
- Retrospective analysis of pediatric glaucoma inpatients from 2017-2020.
- Inclusion of data on patient demographics, glaucoma subtypes, surgical procedures, and outcomes.
- Analysis of intraocular pressure (IOP), re-operation rates, and visual acuity.
Main Results:
- 239 cases (276 eyes) of pediatric glaucoma were analyzed, with a higher prevalence in boys.
- Primary congenital glaucoma (PCG) was the most common type, followed by traumatic glaucoma.
- Trabeculotomy (Trab) and microcatheter-assisted 360° trabeculotomy (MAT) were the most frequent surgeries, with varying IOP and re-operation rates across subtypes.
Conclusions:
- PCG, juvenile open-angle glaucoma (JOAG), and traumatic glaucoma are prevalent pediatric glaucoma subtypes in central China.
- Trab and MAT combined with Trab are common surgical interventions.
- Pediatric amblyopia requires attention post-surgery; enhanced public education on early diagnosis and prevention is essential.
Purpose:
We aimed to describe the characteristics, epidemiology, management, and outcomes of glaucoma in pediatric patients in central China.
Methods:
This study retrospectively analyzed inpatients with pediatric glaucoma at Henan Provincial People's Hospital, Henan Eye Institute, and Henan Eye Hospital between 2017 and 2020.
Results:
Overall, 239 cases (276 eyes) of pediatric glaucoma in patients, comprising 87 girls (36.40%) and 152 boys (63.60%) were analyzed. The mean age was 6.65 ± 4.46, and 2.93% of the patients had a family history of glaucoma. Primary congenital glaucoma (PCG) was the most common type of glaucoma, followed by traumatic glaucoma in 8.33% of the patients, which was considered secondary glaucoma. The most common signs and symptoms were elevated intraocular pressure (IOP) and eye pain. Trabeculotomy (Trab) and microcatheter-assisted 360° trabeculotomy (MAT) combined with Trab were the most commonly performed surgeries. The IOP of patients with PCG, juvenile open-angle glaucoma (JOAG), and secondary glaucoma were 15.27 ± 7.48 mmHg, 17.16 ± 10.05, and 18.65 ± 8.55, respectively, at the final follow up. The rate of re-operations in patients with PCG, JOAG, and secondary glaucoma were 9.15%, 6.78%, and 4.69%, respectively. The mean visual acuity of the eyes with PCG, JOAG, and secondary glaucoma was 0.79 ± 0.68, 0.51 ± 0.48, and 0.53 ± 0.50, respectively.
Conclusion:
PCG, JOAG, and traumatic glaucoma were the most prevalent subtypes in patients with pediatric glaucoma in central China. Trab and MAT combined with Trab were the most common interventions used in this study. Pediatric amblyopia might require full attention during the entire treatment, especially after glaucoma surgery. Effective preventive measures and more public education on glaucoma prevention and the importance of early diagnosis and treatment is necessary.
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