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Related Experiment Video

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Effects of Different Oligosaccharides on Growth Performance and Intestinal Function in Broilers.

Ling Chang^1,2,3, Yanan Ding^1,2,3, Yushi Wang^1,2,3

¹College of Animal Science and Technology, Hunan Agricultural University, Changsha, China.

Frontiers in Veterinary Science

|April 18, 2022

Summary

Oligosaccharides like raffinose (RFO) and chitooligosaccharide (COS) enhance broiler growth and intestinal health. These feed additives improve immune response, antioxidant capacity, and gut microbiota diversity in chickens.

Keywords:

broiler chitooligosaccharide gut microbiota isomalto-oligosaccharide raffinose oligosaccharide

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Area of Science:

Animal Science
Nutrition
Immunology

Background:

Broiler production relies on optimal growth and health.
Intestinal integrity and immune function are crucial for broiler well-being.
Alternative feed additives are sought to replace antibiotics.

Purpose of the Study:

To evaluate the impact of different oligosaccharides on broiler growth performance.
To assess the effects of oligosaccharides on intestinal morphology and immune markers.
To investigate the influence of oligosaccharides on gut microbiota composition and short-chain fatty acids.

Main Methods:

360 yellow-feather chickens were divided into 5 groups.
Groups received a basal diet with chlortetracycline (ANT), isomalto-oligosaccharide (IMO), raffinose oligosaccharide (RFO), or chitooligosaccharide (COS).
Growth, serum immune parameters, intestinal histology, ileum microbiota, and cecal volatile fatty acids were analyzed over 56 days.

Main Results:

Raffinose oligosaccharide (RFO) and chitooligosaccharide (COS) significantly improved average daily gain and feed intake.
Oligosaccharides increased serum IgM, T-SOD, and GSH-Px levels, and enhanced intestinal barrier protein expression (ZO-1, claudin-1).
Dietary oligosaccharides increased villus height, villus height/crypt depth ratio, ileum sIgA, and cecal valeric acid, with varying effects on microbial richness.

Conclusions:

Oligosaccharides supplementation positively impacts broiler growth performance.
Dietary oligosaccharides enhance immune function and antioxidant capacity in broilers.
Oligosaccharides improve intestinal health by modulating morphology, barrier function, and microbiota.