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Highly selective and sensitive 'on-off' fluorescent chemosensor for Fe3+ ions crafted by benzofuran moiety in both
P Madhu1,2, P Sivakumar3, Rajendran Sribalan4
1Research and Development Centre, Bharathiar University, Coimbatore, Tamil Nadu, India.
Abstract:
A benzofuran glycinamide-based chemosensor, 3-(2-([4-fluorobenzyl]amino)acetamido)benzofuran-2-carboxamide (BGA) was developed and synthesized for the selective and sensitive detection of Fe3+ ions. The photophysical properties of the probe BGA were studied using UV-visible light absorption and fluorescence spectrophotometers. The chemosensor BGA showed a marked 'on-off' fluorescence response towards Fe3+ ions in the presence of other metal ions in DMSO/H2 O solution (9/1, v/v). The very low limits of detection (LOD) were calculated to be 10 nM and 43 nM using UV-visible light absorption and fluorescence spectrophotometers, respectively. Job's plot analysis revealed the formation of a BGA-Fe3+ complex with a 1:1 binding stoichiometry ratio using UV-visible light spectroscopy. The sensing mechanism was also demonstrated using density functional theory calculation.
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