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Acute intermittent hemodialysis management in childhood: A single center experience
Tülin Güngör1, Evrim Kargın Çakıcı1, Fatma Yazılıtaş1
1Department of Pediatric Nephrology, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey.
Insights
Glomerular diseases are the primary cause of acute kidney injury (AKI) in children requiring acute intermittent hemodialysis (IHD). These conditions significantly increase the risk of progressing to chronic kidney disease (CKD).
Area of Science:
- Pediatric Nephrology
- Renal Medicine
- Critical Care
Background:
- Acute intermittent hemodialysis (IHD) is a critical treatment for pediatric patients with acute kidney injury (AKI).
- Understanding the indications, characteristics, and outcomes of IHD in children is essential for optimizing care.
Purpose of the Study:
- To identify common indications for acute IHD in pediatric patients.
- To analyze the procedure's characteristics, associated complications, and patient prognosis.
- To investigate the etiological factors contributing to AKI in children.
Main Methods:
- A retrospective study involving 102 pediatric patients (0-18 years) requiring acute dialysis.
- Patients were treated with IHD for acute kidney injury.
- Data on AKI etiology, treatment, complications, and outcomes were collected and analyzed.
Main Results:
- Glomerular diseases accounted for 56% of AKI etiologies in the studied pediatric population.
- A significant association (p=0.01) was found between glomerular disease and the risk of progression to chronic kidney disease (CKD).
- 8.6% of surviving patients progressed to end-stage renal disease.
Conclusions:
- Glomerular diseases are the leading cause of AKI in children requiring IHD.
- Glomerular disease is an independent risk factor for progression to CKD in pediatric patients, irrespective of age, gender, or timing of renal replacement therapy initiation.
Introduction:
The objective of this study was to determine the common indications of acute intermittent hemodialysis (IHD) treatment in childhood and to assess the characteristics of the procedure, complications, and prognosis.
Methods:
The study included 102 patients aged between 0 and 18 years, who had been acute dialysis indication and treated with IHD.
Results:
In terms of acute kidney injury (AKI) etiology, glomerular diseases were prominent in 56% of the patients, and 8.6% of surviving patients progressed to end-stage renal disease. Regarding the cause of AKI, having the glomerular disease was determined to be directly associated (p = 0.01) with the risk of progression to chronic kidney disease (CKD) regardless of age, gender, onset time of renal replacement therapy.
Conclusion:
Glomerular diseases were the most common in AKI etiology and were associated with the progression to CKD, independent of age, gender and the time of IHD onset in our study.
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