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Updated: Sep 26, 2025

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
Published on: September 26, 2019
Studies on stratum corneum metabolism: function, molecular mechanism and influencing factors
Qian Jiao1, Lizhi Yue2, Leilei Zhi3
1Key Laboratory of Cosmetic of China National Light Industry, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing, China.
Background:
Stratum corneum is located in the outermost layer of the skin and is the most important part of the skin barrier. Stratum corneum mainly contains keratinocytes, lipids, and desmosomes. Their normal metabolic process is closely related to the function of skin barrier.
Aims:
This paper reviews the structure and function of stratum corneum, influencing factors, skin diseases, and common solutions.
Methods:
An extensive literature search was conducted on the structure and function of stratum corneum, influencing factors, skin diseases, and common solutions.
Results:
This paper reviews the structure and function of stratum corneum and the influence of various factors on stratum corneum metabolism. At the same time, the existing skin problems, skin diseases, and common solutions are summarized.
Conclusions:
This information will help to understand the function, molecular mechanism, and influencing factors of stratum corneum metabolism, and provide new ideas for stratum corneum health management and cosmetic research and development.
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