Selvester Score May Be a Predictor of ICD Therapies in Patients with Non-Ischemic Dilated Cardiomyopathy
Mevlut Serdar Kuyumcu1, Mehmet Hakan Uzun2, Yasin Ozen3
1Department of Cardiology, Isparta Suleyman Demirel University, Faculty of Medicine, Isparta,Turkey.
Insights
A high Selvester score, a measure of ventricular scar tissue, predicts implantable cardioverter-defibrillator (ICD) therapies in dilated cardiomyopathy (DCM) patients. This non-invasive method aids in treatment decisions for DCM.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- The efficacy of implantable cardioverter-defibrillators (ICDs) in non-ischemic dilated cardiomyopathy (DCM) remains debated.
- Cardiac magnetic resonance (CMR) studies suggest a link between ventricular scar tissue and ICD shocks.
Purpose of the Study:
- To investigate the relationship between the Selvester score, a measure of ventricular scar, and ICD therapies in DCM patients.
- To determine if the Selvester score can predict ICD therapies in this population.
Main Methods:
- Retrospective analysis of 48 DCM patients who received ICDs.
- Comparison of Selvester scores between patients who received ICD therapy (n=10) and those who did not (n=38).
Main Results:
- Patients receiving ICD therapy had significantly higher Selvester scores (P<0.001).
- A strong positive correlation (r=0.843, P=0.002) was found between Selvester score and ICD shock therapy.
- Selvester score independently predicted ICD therapy (P=0.004) and showed high diagnostic accuracy (AUC, P<0.001).
Conclusions:
- A high Selvester score is a significant predictor of ICD therapies in DCM patients.
- The Selvester score, an inexpensive and non-invasive metric, can assist in clinical decision-making for ICD implantation in DCM.
Introduction:
The benefit of implantable cardioverter-defibrillator (ICD) in patients with non-ischemic dilated cardiomyopathy (DCM) is still an issue under discussion. Studies examining the relationship between ventricular scar tissue and ICD shock with cardiac magnetic resonance (CMR) are promising. CMR studies have shown that ventricular scar tissue size and Selvester score show a correlation. In the light of this information, this study aimed to investigate the potential relationship between Selvester score and ICD therapies.
Methods:
The study included 48 patients who had undergone ICD implantation with a diagnosis of DCM and who had undergone routine 6-month ICD control in outpatient clinic controls between December 2018 and October 2019. Selvester score and other data were compared between patients who received ICD therapy (n=10) and those who did not (n=38).
Results:
Selvester score (P<0.001) was higher in ICD therapy group. Positive correlation was found between ICD shock therapy and Selvester score (P=0.002, r=0.843). Selvester score was detected as an independent predictor for ICD therapy after multiple linear regression analysis (P=0.004). Receiver operating characteristic curve analysis showed that Selvester score (P<0.001) was a significant predictor of ICD therapy. Selvester score cutoff points of 5 for were calculated to estimate ICD therapy, with a sensitivity of 100% and specifity of 81%.
Conclusion:
In our study, it was found that a high Selvester score may be a predictor for ICD therapies in patients with DCM. As an inexpensive and non-invasive method, Selvester score can help in the decision-making in these patients.
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