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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

4.1K

MR -specific characteristics of left ventricular noncompaction and dilated cardiomyopathy

Zsófia Gregor1, Anna Réka Kiss1, Kinga Grebur1

  • 1Heart and Vascular Center of Semmelweis University, Budapest, Városmajor utca 68, Budapest 1122, Hungary.

International Journal of Cardiology
|April 18, 2022
PubMed

Insights

Cardiac MRI reveals higher trabeculated papillary muscle mass and lower apical circumferential strain in left ventricular noncompaction (LVNC) compared to dilated cardiomyopathy (DCM). These findings aid in differentiating these cardiac conditions.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Differentiating dilated cardiomyopathy (DCM) and left ventricular noncompaction (LVNC) is challenging in cardiac imaging.
  • Left ventricular (LV) characteristics require detailed comparison for accurate diagnosis.

Purpose of the Study:

  • To compare cardiac MRI characteristics of the left ventricle in patients with DCM and LVNC.
  • To identify imaging parameters that can distinguish between DCM and LVNC.

Main Methods:

  • Retrospective study including 31 nonischemic DCM patients, 42 LVNC patients, and 42 controls.
  • LV volumetric, functional, and myocardial mass parameters measured using threshold-based techniques.
  • Global and segmental strain, and rotational patterns analyzed with feature-tracking strain analysis.

Main Results:

  • Trabeculated and papillary muscle mass (TPMi) was significantly higher in LVNC patients compared to DCM patients.
  • Global longitudinal and circumferential strains were similar between DCM and LVNC groups but worse than controls.
  • Apical circumferential strain was significantly lower in the LVNC group compared to the DCM group.

Conclusions:

  • Despite similarities in volumetric and global strain parameters, LVNC shows higher TPMi and lower apical circumferential strains than DCM.
  • These differences may relate to the trabeculated apical morphology characteristic of LVNC.
  • Cardiac MRI offers distinct parameters for differentiating LVNC from DCM.
Abstract

Keywords:
Dilated cardiomyopathyFeature-trackingLeft ventricular noncompactionRotationStrainTrabeculation

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