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Author Spotlight: Exploring Cellular Zinc Regulation Through ZnT1 Functionality
Published on: June 2, 2023
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Zinc in dermatology.
Tamara Searle1, Faisal R Ali2, Firas Al-Niaimi3
1North Middlesex University Hospital, London, UK.
The Journal of Dermatological Treatment
|April 19, 2022
Summary
This review highlights zinc
Area of Science:
- Dermatology and Cutaneous Medicine
- Pharmacology and Therapeutics
Background:
- Zinc possesses antioxidant and immunomodulatory properties.
- These properties are linked to its effectiveness in various dermatological conditions.
Purpose of the Study:
- To review the existing literature on zinc's applications in dermatology.
- To specifically examine zinc's role in acne vulgaris, hair loss, hidradenitis suppurativa, leishmaniasis, and warts.
Main Methods:
- A literature review was conducted using MEDLINE.
- Only English-language articles were included.
- Evidence was evaluated using the Oxford Center of Evidence-Based Medicine 2011 guidance.
Main Results:
- Evidence supports zinc's use in infectious conditions like leishmaniasis and warts.
- Evidence supports zinc's use in inflammatory conditions such as acne rosacea and hidradenitis suppurativa.
- Evidence supports zinc's use in hair loss disorders.
Conclusions:
- Zinc is beneficial for several dermatological conditions, including infectious, inflammatory, and hair loss disorders.
- Oral zinc supplementation is recommended for patients with zinc deficiency.
- Further research, including large randomized controlled trials, is needed to explore zinc as a monotherapy.
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