Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Laser-assisted microsurgical anastomosis.

C R Neblett, J R Morris, S Thomsen

    Neurosurgery
    |December 1, 1986
    PubMed
    Summary

    Laser-assisted microvascular anastomosis (LAMA) using a low-power CO2 laser offers a faster alternative to conventional suturing for small vessel repair. Both LAMA and suture techniques show comparable patency and healing, suggesting laser

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Role of Static Displacements in Stabilizing Body Centered Cubic High Entropy Alloys.

    Physical review letters·2021
    Same author

    Curie-Weiss behavior of liquid structure and ideal glass state.

    Scientific reports·2019
    Same author

    Predictive multiphase evolution in Al-containing high-entropy alloys.

    Nature communications·2018
    Same author

    DNA damage emergency: cellular garbage disposal to the rescue?

    Oncogene·2013
    Same author

    The origin of viscosity as seen through atomic level stress correlation function.

    The Journal of chemical physics·2013
    Same author

    The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment.

    Oncogene·2012

    Area of Science:

    • Biomedical Engineering
    • Microsurgery
    • Vascular Surgery

    Background:

    • Conventional microvascular suture anastomosis (CMSA) is time-consuming.
    • Laser-assisted microvascular anastomosis (LAMA) is an emerging alternative.
    • Evaluating LAMA's efficacy and safety in small vessel repair is crucial.

    Purpose of the Study:

    • To compare the duration, patency, and wound healing of LAMA versus CMSA.
    • To assess the potential clinical application of low-energy CO2 laser for microvascular repair.

    Main Methods:

    • Performed 212 end-to-end LAMA and 82 CMSA on rat femoral arteries (mean diameter 1.2 mm).
    • Utilized a low-power CO2 laser (80 mW, 10.6 micron wavelength) for LAMA.
    • Compared procedure duration, patency rates, aneurysm formation, and histological/ultrastructural healing.

    Main Results:

    • LAMA procedures were significantly faster (16 min vs. 27 min, P < 0.05).
    • Patency rates were comparable: 95% for LAMA and 96% for CMSA.
    • Histological and SEM analyses showed similar healing patterns and reendothelialization by 3 weeks; LAMA repair tensile strength matched intact artery at 21 days.

    Conclusions:

    • Low-power CO2 laser-assisted microvascular anastomosis is a viable, faster alternative to CMSA for small vessels.
    • LAMA demonstrates comparable patency and wound healing to conventional suturing.
    • The technique shows promise for clinical application in microvascular surgery.

    Related Experiment Videos