Adult Onset Still's Disease

Area of Science:

• Rheumatology
• Internal Medicine
• Systemic Inflammatory Disorders

Background:

• Adult onset Still's disease (AOSD) is a rare systemic inflammatory disorder with unknown causes.
• Diagnosis is challenging due to the absence of specific tests, necessitating the use of established criteria and exclusion of other conditions.

Observation:

• A 35-year-old female presented with key symptoms including daily high fevers, rash, arthritis, sore throat, itching, elevated white blood cell count (leukocytosis), and high ferritin levels (hyperferritinemia).

Findings:

• The patient was diagnosed with AOSD by fulfilling the Yamaguchi et al. criteria.
• Differential diagnosis was crucial to exclude other potential conditions presenting with similar symptoms.

Implications:

• This case highlights the importance of adhering to diagnostic criteria for AOSD.
• Accurate diagnosis is essential for appropriate management of this rare systemic inflammatory disease.