Related Experiment Video
Updated: Sep 26, 2025

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Association between life-course leisure-time physical activity and prostate cancer
Ruth Argelia Vázquez-Salas1, Luisa Torres-Sánchez2, Marcia Galván-Portillo3
1Cátedra Conacyt, Instituto Nacional de Salud Pública/Instituto Nacional de Salud Pública. Cuernavaca, Morelos, Mexico. argelia.vazquez@insp.mx.
Objective:
To evaluate the association between life-course leisure-time physical activity (PA) and prostate cancer (PC) among males living in Mexico City. Materials and meth-ods. Information from 394 incident PC cases and 794 popula-tion controls matched by age (± 5 years), was analyzed. Using leisure-time PA information at different life stages, life-course PA patterns were constructed. The association between PA and PC was estimated using an unconditional logistic regres-sion model.
Results:
Three life-course PA patterns were identified: low PA (71.0%), moderate PA (22.0%), and high PA (7.0%); this last pattern was characterized by higher levels and consistent PA practice. Compared with inactive males, those in the high PA pattern (OR: 0.50; 95%CI: 0.26-0.93) had significantly lower PC odds.
Conclusion:
Intense and regular PA could reduce the possibility of PC. These results are in accordance with PA World Health Organization rec-ommendations.
Related Concept Videos
Cancer Prevention
Some...
Longitudinal Research
Lifestyle Factors and Health
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Cancer Survival Analysis
mTOR Signaling and Cancer Progression
The mTOR pathway or the...

