Neo-Darwinism must Mutate to survive

Area of Science:

• Evolutionary Biology
• Biochemistry
• Theoretical Physics

Background:

• Darwinian evolution, a 19th-century concept, has evolved significantly.
• Microevolution is empirically verified, but progress in the modern synthesis is limited.
• The concept of 'survival of the fittest' has been central but faces scrutiny.

Purpose of the Study:

• To provide evidence that 'survival of the fittest' is insufficient for macroevolution.
• To challenge the adequacy of the modern synthesis in evolutionary biology.
• To propose a new direction for evolutionary theory, incorporating mathematics and novel concepts.

Main Methods:

• Probabilistic calculations based on microevolutionary data.
• Analysis of the plausibility of macroevolutionary events under current theories.
• Review of existing evolutionary mechanisms and their limitations.

Main Results:

• Macroevolutionary events, including speciation and the Cambrian explosion, are probabilistically highly implausible (10^-50) under 'survival of the fittest'.
• Mechanisms like random genetic drift do not salvage macroevolution based on 'survival of the fittest'.
• Current evolutionary biology faces deficiencies, particularly concerning the limitations of 'survival of the fittest'.

Conclusions:

• A unifying theory for evolutionary biology is needed, potentially modeled after physics' Grand Unified Theory.
• Rigorous mathematical application to empirical discoveries and a shift to 'aeon (life) chemistry' are essential.
• Novel approaches, including self-organization and negentropy, should be explored to address evolutionary deficiencies.