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Updated: Sep 26, 2025

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Recent progress in endoscopic skull base surgery: Functional preservation and multiportal approaches.
Masahiro Kikuchi1, Takayuki Nakagawa1
1Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Kyoto University, 54 Kawaharacho, Shogoin, Sakyoku, Kyoto 606-8507, Japan.
Endoscopic skull base surgery (ESBS) advances enable functional preservation and multiportal techniques for complex pathologies. Ongoing evaluation is crucial for these evolving surgical methods.
Area of Science:
- Neurosurgery
- Otolaryngology
- Skull Base Surgery
Background:
- Endoscopic skull base surgery (ESBS) has evolved significantly over two decades.
- ESBS is increasingly applied to diverse pathologies, including sinonasal malignancies.
- Recent advancements show ESBS efficacy in complete resection with reduced morbidity for complex lesions.
Purpose of the Study:
- To review the evolution of functional preservation in ESBS.
- To explore the development and application of multiportal approaches in ESBS.
- To highlight progress in olfactory function preservation during ESBS.
Main Methods:
- Review of recent studies and surgical techniques in ESBS.
- Analysis of preoperative assessments and surgical advancements.
- Examination of multiportal approaches combining endoscopic endonasal with other endoscopic techniques.
Main Results:
- Improved olfactory function preservation through advanced techniques.
- Demonstrated feasibility of preserving olfaction even with olfactory groove resections.
- Development of multiportal approaches (e.g., transorbital, transmaxillary, transoral) for extensive pathologies.
- Successful resection of complex lesions with limited morbidity using combined approaches.
Conclusions:
- ESBS techniques have advanced, improving functional preservation, particularly olfaction.
- Multiportal approaches extend the reach of endoscopic surgery for complex skull base pathologies.
- These innovative techniques require continued critical evaluation for efficacy and maturation.
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