A multi-parameter persistence framework for mathematical morphology
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Updated: Sep 26, 2025

Morphology-Based Distinction Between Healthy and Pathological Cells Utilizing Fourier Transforms and Self-Organizing Maps
Published on: October 28, 2018
Yu-Min Chung1, Sarah Day2, Chuan-Shen Hu3
1Eli Lilly and Company, Indianapolis, IN, 46225, USA. yumchung@alumni.iu.edu.
Abstract:
The field of mathematical morphology offers well-studied techniques for image processing and is applicable for studies ranging from materials science to ecological pattern formation. In this work, we view morphological operations through the lens of persistent homology, a tool at the heart of the field of topological data analysis. We demonstrate that morphological operations naturally form a multiparameter filtration and that persistent homology can then be used to extract information about both topology and geometry in the images as well as to automate methods for optimizing the study and rendering of structure in images. For illustration, we develop an automated approach that utilizes this framework to denoise binary, grayscale, and color images with salt and pepper and larger spatial scale noise. We measure our example unsupervised denoising approach to state-of-the-art supervised, deep learning methods to show that our results are comparable.
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