Related Experiment Video
Updated: Sep 26, 2025

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
Frailty among Older Adults and Its Distribution in England
D R Sinclair1, A Maharani, T Chandola
1David R Sinclair, National Institute for Health Research (NIHR) Older People and Frailty Policy Research Unit, Population Health Sciences Institute, Newcastle University, Newcastle-upon-Tyne, NE4 5PL, UK, Email address: David.R.Sinclair@newcastle.ac.uk.
Frailty prevalence in England is 8.1%, with significant geographic disparities. Urban and coastal areas show higher frailty rates, necessitating targeted interventions for healthy ageing inequalities.
Area of Science:
- Gerontology
- Public Health
- Spatial Epidemiology
Background:
- Understanding the spatial distribution of frailty is essential for effective health and social care planning.
- Geographic variations in frailty prevalence can highlight areas needing targeted support.
Purpose of the Study:
- To estimate small-area frailty prevalence in older adults across England.
- To investigate differences in frailty prevalence between urban, rural, coastal, and inland regions.
Main Methods:
- Utilized data from the English Longitudinal Study of Ageing (ELSA).
- Employed ordinal logistic regression to predict frailty probability based on age, sex, and area deprivation.
- Applied predicted probabilities to 2020 population projections for district-level frailty prevalence estimation.
Main Results:
- Estimated frailty prevalence in adults aged 50+ in England (2020) was 8.1%.
- Observed a four-fold variation in frailty prevalence between the most and least affected areas.
- Found higher frailty prevalence in urban compared to rural areas, and in coastal compared to inland areas.
Conclusions:
- Significant geographic inequalities in healthy ageing exist in England.
- Older adults in urban and coastal areas experience disproportionately higher frailty.
- Interventions to reduce inequalities in healthy ageing should prioritize urban and coastal regions for maximum impact.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
The Effect of Aging on Tissues
Factors Affecting Illness
For instance, risk factors are connected to illness,...
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Current Trends in Nursing I
Cognitive Development During Adulthood

