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Two cases of ceftriaxone-induced encephalopathy treated by hemoperfusion in hemodialysis patients
Chikao Onogi1, Akinori Osada2, Kentaro Imai2
1Department of Nephrology, Kasugai Municipal Hospital, Kasugai, Japan.
Abstract:
Ceftriaxone is a third-generation cephalosporin commonly used to treat infection. However, encephalopathy is an emerging adverse effect of ceftriaxone infusion. These patients present with various symptoms, including those of neurotoxicity, that typically resolve 1 week after discontinuation of ceftriaxone. We experienced two cases of ceftriaxone-induced encephalopathy that were successfully treated by rapid removal of ceftriaxone by hemoperfusion.
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