Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

2.7K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.7K
Aging01:26

Aging

214
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
214
Bone Disorders01:29

Bone Disorders

4.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
4.0K
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

1.1K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
1.1K
Muscle Recovery and Fatigue01:24

Muscle Recovery and Fatigue

2.8K
Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective...
2.8K
Mitochondria01:37

Mitochondria

15.3K
Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
15.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

AAPM&R guidance statement on platelet rich plasma for knee osteoarthritis.

PM & R : the journal of injury, function, and rehabilitation·2026
Same author

Factors Associated With Functional Outcomes in Former Professional American-Style Football Players With Symptomatic Knee and Hip Osteoarthritis.

Orthopaedic journal of sports medicine·2026
Same author

Sustainable sizing, dispatch, and resilience planning of hybrid microgrids using Arctic Puffin Optimization.

Scientific reports·2026
Same author

American Medical Society for Sports Medicine Orthobiologics Toolkit for Sports Medicine Fellowships.

Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine·2026
Same author

Recombinant human growth hormone (rHGH) for muscle enhancement in knee osteoarthritis: protocol for a pilot, randomised placebo-controlled trial.

BMJ open·2026
Same author

Exceptionally selective voltage-sensor trapping of Na<sub>V</sub>1.5 channels by Mg-protoporphyrin impairs cancer cell migration.

Scientific reports·2026
Same journal

Physical therapists' experiences treating patients with hip joint-related pain: Facilitators and barriers to rehabilitation.

PM & R : the journal of injury, function, and rehabilitation·2026
Same journal

Adherence to and perceptions of a Peruvian osteoarthritis clinical practice guideline among physiatrists and residents.

PM & R : the journal of injury, function, and rehabilitation·2026
Same journal

Immediate changes in thoracic spine mobility after repetitive pitching in high school baseball players: A randomized controlled trial.

PM & R : the journal of injury, function, and rehabilitation·2026
Same journal

Longitudinal improvements in comfort, mobility, and quality of life with adjustable-volume prosthetic sockets.

PM & R : the journal of injury, function, and rehabilitation·2026
Same journal

Physical activity and exercise participation-Impact on motor and non-motor outcomes in early-stage Parkinson disease: A cross-sectional study.

PM & R : the journal of injury, function, and rehabilitation·2026
Same journal

Innovative technologies for gait rehabilitation in incomplete spinal cord injury: A systematic review and meta-analysis.

PM & R : the journal of injury, function, and rehabilitation·2026
See all related articles

Related Experiment Video

Updated: Sep 26, 2025

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
12:59

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Published on: July 5, 2017

12.7K

The aging athlete.

Michael Catapano1,2, Marwa Ahmed1,2, Rebecca G Breslow3

  • 1Department of Physical Medicine and Rehabilitation, Harvard Medical School, Charlestown, Massachusetts, USA.

PM & R : the Journal of Injury, Function, and Rehabilitation
|April 20, 2022
PubMed
Summary
This summary is machine-generated.

Active aging athletes over 60 face unique health risks despite exercise benefits. This review covers their specific physiology, injury risks, and prevention strategies for older athletes.

More Related Videos

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
07:27

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

Published on: October 6, 2016

10.4K
Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease
10:19

Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease

Published on: August 22, 2014

14.4K

Related Experiment Videos

Last Updated: Sep 26, 2025

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
12:59

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Published on: July 5, 2017

12.7K
Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
07:27

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

Published on: October 6, 2016

10.4K
Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease
10:19

Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease

Published on: August 22, 2014

14.4K

Area of Science:

  • Sports Medicine
  • Gerontology
  • Exercise Physiology

Background:

  • Aging athletes (60+) are an expanding demographic valuing lifelong physical activity.
  • Existing guidelines for younger athletes are often extrapolated, lacking specificity for older adults.
  • Unique cardiovascular, metabolic, and musculoskeletal considerations exist for this population.

Purpose of the Study:

  • To review the distinct physiology of aging athletes.
  • To identify specific medical conditions and injury risks in this group.
  • To discuss prevention, treatment, and future research directions.

Main Methods:

  • Literature review focusing on cardiovascular and muscular physiology in aging athletes.
  • Analysis of injury risks and medical conditions pertinent to older active individuals.
  • Synthesis of current prevention and treatment strategies.

Main Results:

  • Aging influences cardiovascular and muscular systems, altering injury susceptibility.
  • Specific medical conditions and injury patterns are associated with aging athletes.
  • Generalizable prevention and treatment approaches are discussed, highlighting knowledge gaps.

Conclusions:

  • Understanding the unique physiology of aging athletes is crucial for safe participation.
  • Tailored guidelines and interventions are needed to address their specific health risks.
  • Further research is essential to optimize the health and performance of older athletes.