Related Experiment Video
Updated: Sep 26, 2025

12:17
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
11.5K
Aortic root thrombus causing non-ST elevation myocardial infarction after left ventricular assist device.
Akhil S Kallur1, Fred Bien-Aime1, Tariq Sallam1
1Internal Medicine, MedStar Washington Hospital Center, Washington, D.C., USA.
Perfusion
|April 20, 2022
Summary
A rare aortic root thrombus (AT) complication occurred in a patient with a left ventricular assist device (LVAD). This case highlights the need for multidisciplinary management of such rare thromboembolic events in LVAD patients.
Area of Science:
- Cardiology
- Medical Devices
Background:
- Left ventricular assist devices (LVADs) are crucial for managing advanced heart failure.
- Patients with LVADs require anticoagulation to prevent thrombotic complications.
- Ischemic cardiomyopathy is a common indication for LVAD implantation.
Observation:
- A 61-year-old male with a history of ischemic cardiomyopathy and LVAD presented with non-ST elevation myocardial infarction.
- Despite warfarin therapy, the patient had a subtherapeutic INR of 1.6.
- Left heart catheterization revealed an extensive aortic root thrombus (AT).
Findings:
- Aortic root thrombus (AT) is an uncommon cause of thromboembolic events in long-term LVAD patients.
- Thrombotic events in LVAD patients include pump thrombosis, cerebrovascular accidents, and heparin-induced thrombocytopenia.
- This case presents a rare instance of AT in an LVAD patient on anticoagulation.
Implications:
- Management strategies for AT in LVAD patients are not well-established.
- A multidisciplinary approach is suggested for managing this rare complication.
- Conservative treatment should be considered for patients with aortic root thrombus and LVAD.
Related Concept Videos
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
67
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
67
Aortic Regurgitation I: Introduction
59
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
59
Aortic Regurgitation III: Medical Management
56
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
56
Aneurysm III: Interprofessional Care
37
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
37

