SMALL AS WELL AS LARGE COLORECTAL LESIONS ARE EFFECTIVELY MANAGED BY ENDOSCOPIC MUCOSAL RESECTION TECHNIQUE

Area of Science:

• Gastroenterology
• Endoscopy
• Colorectal Surgery

Background:

• Endoscopic mucosal resection (EMR) is a practical treatment for superficial colorectal lesions.
• EMR is suitable for lesions of all sizes, including those 20 mm or larger.

Purpose of the Study:

• To assess the efficacy of Endoscopic Mucosal Resection (EMR).
• To analyze adverse events and recurrence rates associated with EMR.

Main Methods:

• A review of 430 lesions removed via EMR in 404 patients.
• Lesions were categorized by morphology, size, location, and histology.
• En bloc resection for lesions <20 mm and piecemeal EMR (p-EMR) for lesions ≥20 mm were compared.

Main Results:

• Most lesions (84%) were <20 mm; 16% were ≥20 mm.
• Neoplastic histology was observed in 96% of lesions.
• Piecemeal EMR (p-EMR) was linked to increased adverse events (3.3%) and recurrence (5.2%), especially with advanced histology.

Conclusions:

• EMR is a highly effective treatment for superficial colorectal lesions.
• EMR is a viable option for managing large colorectal lesions.
• Careful consideration of p-EMR is needed due to potential for higher adverse events and recurrence.