Related Experiment Video
Updated: Sep 26, 2025

26:41
Perspectives on Neuroscience
Published on: July 31, 2007
5.1K
Pain Science in Practice: What Is Pain Neuroscience? Part 2
The Journal of Orthopaedic and Sports Physical Therapy
|April 20, 2022
Abstract
Synopsis:
Biomechanical explanations for musculoskeletal pain are abundant and have been used for many years; however, researchers and clinicians are moving toward neuroscience-based explanations to study and explain them. This article discusses some specific mechanisms, commonly used in pain medicine, and their somewhat less specific but equally important role in nonpharmacological management of musculoskeletal pain. The article also explains the role of different receptors and how they relate to clinical conditions. J Orthop Sports Phys Ther 2022;52(4):166-168. doi:10.2519/jospt.2022.10994.
Related Concept Videos
Neuroplasticity
871
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
871
Postsynaptic Potential (PSP)
3.5K
Postsynaptic potential (PSP) refers to a change in the electrical potential of a neuron when neurotransmitters released by presynaptic neurons bind to postsynaptic receptors. This potential can either be excitatory, leading to depolarization and ultimately action potential generation, or inhibitory, leading to hyperpolarization and suppression of the postsynaptic neuron.
There are two types of receptors: ionotropic and metabotropic.
The ionotropic receptor is the membrane protein that has an...
There are two types of receptors: ionotropic and metabotropic.
The ionotropic receptor is the membrane protein that has an...
3.5K

