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RDW a Predictor in OP Poisoning.

Adithya A¹, Adarsh Ls¹

¹JSS Medical College, JSSAHER, Mysuru.

The Journal of the Association of Physicians of India

|April 21, 2022

Summary

This summary is machine-generated.

Red cell distribution width (RDW) can predict outcomes in organophosphate compound (OPC) poisoning. Elevated RDW levels indicate a higher likelihood of complications or mortality in OPC poisoning patients.

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Area of Science:

Clinical Toxicology
Hematology

Background:

Organophosphate compound (OPC) poisoning is a significant public health issue in developing countries like India.
Novel prognostic markers are needed to assess outcomes in OPC poisoning.
Red cell distribution width (RDW) has been proposed as a potential predictor, but studies are largely retrospective.

Purpose of the Study:

To prospectively evaluate the association between RDW and patient outcomes in organophosphate poisoning.
To determine if RDW can serve as a predictor of complications and mortality in OPC poisoning.

Main Methods:

A prospective study of 115 patients admitted with OPC poisoning.
Collected complete hemogram (including RDW) and serum cholinesterase levels.
Recorded patient demographics, poisoning circumstances, and vital signs.

Main Results:

The mean age of patients was 36.73 years, with 80% males.
Patients were categorized into: no complications (52%), complications (27%), and death (20.9%).
RDW showed 87.5% sensitivity and 51.65% specificity for predicting outcomes, with elevated levels in complicated and fatal cases.

Conclusions:

RDW is a significant predictor of outcomes in organophosphate poisoning, with elevated levels associated with complications and mortality.
RDW was not found to be an independent predictor of mortality in this study.