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Updated: Sep 26, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

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Design and Synthesis of Conformationally Diverse Pyrimidine-Embedded Medium/Macro- and Bridged Cycles via Skeletal

Yoona Choi1, Subin Lee1, Heejun Kim1

  • 1CRI Center for Chemical Proteomics, Department of Chemistry, Seoul National University, Seoul, South Korea.

Frontiers in Chemistry
|April 21, 2022
PubMed

Keywords:
bridged cycleconformational diversitymacrocyclemedium cyclepolyheterocyclepyrimidineskeletal transformation

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