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Updated: Sep 26, 2025

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

Sprayable hydrogel for biomedical applications.

Yingying Liao¹, Luoyijun Xie¹, Jiahui Ye¹

¹The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China. shillei@mail.sysu.edu.cn.

Biomaterials Science

|April 21, 2022

Summary

This summary is machine-generated.

Sprayable hydrogels, especially from natural polymers, offer biocompatible solutions for wound management and cancer therapeutics. This review highlights recent advances, properties, and applications of these promising biomaterials.

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Area of Science:

Biomaterials Science
Polymer Chemistry
Regenerative Medicine

Background:

Polymeric hydrogels show significant promise for biomedical applications.
Sprayable hydrogels are gaining attention due to their biocompatibility, degradability, tunable mechanics, and rapid spray-filming capabilities.
Natural polymers like polysaccharides and proteins are key components in advanced hydrogel development.

Purpose of the Study:

To review recent advancements in sprayable hydrogel systems.
To highlight the properties and diverse applications of sprayable hydrogels.
To discuss future research directions and challenges in the field.

Main Methods:

Literature review focusing on sprayable hydrogel systems.
Analysis of hydrogel properties including biocompatibility, degradability, and mechanical tunability.
Exploration of applications in wound management, postoperative adhesion, and cancer therapeutics.

Main Results:

Sprayable hydrogels derived from natural polymers exhibit excellent biocompatibility and tunable properties.
Recent advances have expanded their utility in critical biomedical areas.
Key applications include advanced wound dressings, prevention of postoperative adhesions, and targeted cancer therapies.

Conclusions:

Sprayable hydrogels represent a significant advancement in biomaterials for medical use.
Their versatility and ease of application offer solutions for complex clinical challenges.
Further research is needed to overcome existing challenges and fully realize their therapeutic potential.