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Published on: September 20, 2018
Occult prosthetic aortic valve endocarditis caused by Propionibacterium acnes: a case report
M Servito1, A L Fernández2, S Culhane1
1Kingston Health Science Centre, Kingston, Ontario, Canada.
Abstract:
We present an unusual case of occult mechanical aortic valve endocarditis caused by Propionibacterium acnes (P. acnes), which occurred five years after the initial cardiac surgical procedure. The only potential source of this infection from the patient's past medical history was a gastric band removal followed by a gastric bypass surgery, which was performed two years prior to her redo cardiac procedure. The patient's main presenting symptom was progressive dyspnoea with worsening of gradients across the mechanical aortic valve. Of note, she had no cardinal symptoms of infection. The patient underwent redo bioprosthetic aortic valve replacement with aortic root replacement. Prosthetic valve cultures grew P. acnes, while blood cultures remained negative. She was started on intravenous antibiotics for six weeks and her postoperative course was uneventful. She remained symptom-free six months postoperatively. This case opens the discussion for the importance of administering antibiotics prophylaxis for endocarditis in patients with prosthetic heart valves undergoing gastric procedures.
Insights
This case highlights a rare mechanical aortic valve endocarditis caused by Propionibacterium acnes (P. acnes). It suggests antibiotic prophylaxis for patients with prosthetic valves undergoing gastric procedures.
Area of Science:
- Cardiology
- Infectious Diseases
- Surgical Infections
Background:
- Prosthetic valve endocarditis (PVE) is a serious complication following cardiac surgery.
- Propionibacterium acnes (P. acnes) is an uncommon cause of PVE, often associated with delayed onset infections.
Observation:
- A patient presented with progressive dyspnea and worsening aortic valve gradients five years post-surgery.
- Past medical history included gastric band removal and bypass surgery two years before cardiac reoperation.
- No cardinal symptoms of infection were present during initial presentation.
Findings:
- Occult mechanical aortic valve endocarditis caused by P. acnes was diagnosed.
- P. acnes was isolated from prosthetic valve cultures, but blood cultures were negative.
- The patient successfully underwent redo bioprosthetic aortic valve replacement and recovered after a six-week antibiotic course.
Implications:
- This case underscores the importance of considering P. acnes in delayed-onset PVE, especially after gastrointestinal procedures.
- It raises the question of antibiotic prophylaxis for endocarditis in patients with prosthetic heart valves undergoing gastric surgery.
- Highlights the need for a thorough patient history, including prior surgeries, in diagnosing PVE.
Related Concept Videos
Endocarditis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis III: Medical Management
Endocarditis IV: Nursing Management
Aortic Regurgitation I: Introduction
Rheumatic Heart Disease I: Introduction

