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Current Landscape of Coccidioidomycosis
Ryan Boro1, Prema C Iyer1, Maciej A Walczak2
1Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Journal of Fungi (Basel, Switzerland)
|April 21, 2022
Summary
Valley fever (coccidioidomycosis) is spreading and increasing. This review covers its epidemiology, treatments, diagnostics, and interactions with COVID-19, highlighting future research needs.
Area of Science:
- Mycology
- Infectious Diseases
- Epidemiology
Background:
- Coccidioidomycosis, or Valley fever, is a fungal infection endemic to the southwestern US.
- Increasing geographic range and prevalence of coccidioidomycosis are observed.
- The disease presents diagnostic challenges and potential overlaps with COVID-19.
Purpose of the Study:
- To review the latest information on coccidioidomycosis.
- To cover epidemiology, pharmaceutical treatments, diagnostic concerns, and COVID-19 interactions.
- To identify future research and development directions.
Main Methods:
- Literature review of recent studies on coccidioidomycosis.
- Compilation of data on disease trends, prevalence, and geographical spread.
- Analysis of current and emerging therapeutic and diagnostic strategies.
Main Results:
- Coccidioidomycosis is expanding beyond its traditional endemic areas.
- New pharmaceutical agents are in development for treatment.
- Understanding the interplay between coccidioidomycosis and COVID-19 is crucial, especially in vulnerable populations.
Conclusions:
- Current diagnostic and therapeutic strategies for coccidioidomycosis require ongoing evaluation.
- Further research is needed to address the increasing prevalence and geographical spread.
- Development of novel treatments and improved diagnostics is essential for managing coccidioidomycosis.
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