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Related Experiment Video

Updated: Sep 26, 2025

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Ultrasound-Guided Compression Method Effectively Counteracts Russell's Viper Bite-Induced Pseudoaneurysm.

Subramanian Senthilkumaran1, Stephen W Miller2, Harry F Williams3

  • 1Emergency Department, Manian Medical Centre, Erode 638001, India.

Toxins
|April 21, 2022
PubMed
Summary

Russell's viper bites can cause pseudoaneurysms, a rare arterial condition. Ultrasound-guided compression (USGC) effectively treated this complication in two patients, demonstrating a successful non-surgical approach.

Keywords:
Russell’s vipercolour Doppler imagingpseudoaneurysmsnakebite envenomationulnar arteryultrasound-guided compression

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Area of Science:

  • Vascular Surgery
  • Toxicology
  • Herpetology

Background:

  • Russell's viper (Daboia russelii) envenomation causes significant mortality and morbidity in India.
  • Known effects include coagulopathy, myotoxicity, nephrotoxicity, and neurotoxicity.
  • Rare complications like priapism and splenic rupture have been documented.

Purpose of the Study:

  • To report the first cases of pseudoaneurysm (PA) following Russell's viper bites.
  • To evaluate the efficacy of ultrasound-guided compression (USGC) in treating PA post-envenomation.

Main Methods:

  • Documentation of two clinical cases of Russell's viper bites complicated by PA.
  • Treatment of PA using ultrasound-guided compression (USGC), with or without thrombin.
  • Follow-up with clinical examination and ultrasound scans to confirm resolution.

Main Results:

  • Pseudoaneurysm (PA) developed in two patients despite receiving antivenom treatment for Russell's viper bites.
  • Ultrasound-guided compression (USGC), alone or with thrombin, successfully treated the PA in both cases.
  • Patients achieved complete recovery without PA recurrence, confirmed by follow-up scans.

Conclusions:

  • Pseudoaneurysm (PA) is a rare but potential complication of Russell's viper bites.
  • Ultrasound-guided compression (USGC) is an effective, non-surgical treatment for PA in snakebite victims.
  • Increased awareness among healthcare professionals regarding PA and USGC in viper envenomation is recommended.